Volume 20, Issue 4, December 2004

Feature Article

PREGNANCY IN ADOLESCENTS WITH TYPE 1 DIABETES

Bronwen G. Brindley, MD
Lois Jovanovic, MD
Sansum Diabetes Research Institute
Santa Barbara, California

Adolescence is a time of many changes. For an adolescent with type 1 diabetes mellitus (T1DM), change means becoming more self-reliant in dealing with chronic illness. Rebellion, acting out, and the desire to be "normal" may drive the adolescent with chronic disease to make poor choices.1,2 Such choices may have detrimental effects on dietary intake, medication usage, and social behavior.1,3 For diabetic adolescents, low self-esteem and depression may contribute to behavior resulting in an unplanned pregnancy. This is of high risk to both the woman and fetus and is associated with high rates of congenital malformations, spontaneous abortions, and stillbirths.4,5 Additionally, the pregnancy can complicate diabetes. Retinopathy and nephropathy may worsen,6,7 and preeclampsia and hypertension of pregnancy occur more frequently.8 However routine physician visits usually focus on the state of the disease without addressing the sexual habits and/or contraceptive options for adolescents. Planned pregnancies are not relevant for most teenagers, thus pregnancy is usually unintended.9,10 Medical intervention usually begins after embryogenesis and organogenesis,11 and the level of glycemic control, is often sub optimal at the time of conception and early development.9,12 This review aims to bring to the attention of pediatric endocrinologists the importance of this issue.

 

From the Editor's Desk

Abstracts

Celiac Autoimmunity, Celiac Disease and Growth

Congenital Adrenal Hyperplasia, Antley-Bixler Syndrome and Mutant P450 Oxidoreductase

Prevention of Progression from Pubarche to Polycystic Ovary Syndrome

Improving Accuracy of Linear Growth Measurements

Stature and Psychosocial Adjustment in Adulthood

The Marfan Syndrome – TFG-ß Connection

Somatostatin: New Effects on the GH-IGF Axis

ADHD Treatment & Growth

Cornelia de Lange Syndrome Gene Mutations

Metabolic Syndrome in Obese Children

Index

Index of Volume 20

E-Abstracts (Abstracts Online)

Bardet-Biedl Syndrome – Cellular Disorganization

Filamin B Mutations Disrupt Skeletogenesis in Bone Dysplasias

Raloxifene and Tamoxifen Treatment of Pubertal Gynecomastia