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Neonatal Exendin-4 Prevents the Development of Diabetes in the Intrauterine Growth Retarded Rat

Volume 19, Issue 4, 2003
 

Body weight at 2 weeks and 3 months

 

Treatment group

2 weeks (g)

3 months (g)

 

(n=9)

(n=7)

Control vehicle

27.7 ± 0.3

331.7 ± 7.0

Control Ex-4

22.2 ± 0.6*

305.3 ± 12.7*

IUGR Ex-4

13.8 ± 0.7†

311.0 ± 4.0†

IUGR vehicle

17.2 ± 0.7‡

351.7 ± 26.2‡

 
Data are means ± SE. *P < 0.05 control Ex-4 vs. control vehicle; †P < 0.05 IUGR Ex-4 vs. IUGR vehicle; ‡P < 0.05 control vehicle vs. IUGR vehicle.
 
Adapted from Stoffers DA, et al.  Diabetes 2003;52:734-740.
 
 
 
 
 
 
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