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Table

Hyperzincaemia and Hypercalprotectinaemia: A New Disorder of Zinc Metabolism

Volume 19, Issue 2, 2003
 

Table - Clinical and Laboratory Data of Patients

 

 

Patient 1

Patient 2

Patient 3

Patient 4

Patient 5

Age (years)

18

9

14

35

21

Sex

M

F

M

F

M

Growth failure

<3rd percentile

<3rd percentile

<3rd percentile

Normal

Normal

Hepatosplenomegaly

Yes

Yes

Yes

Yes

Yes

Dermatological symptoms

Vasculitis

None

None

Vasculitis, eczema

Vasculitis, furuncules ulcers

Rheumatic symptoms

Arthritis

Arthritis

Arthritis

Arthritis, uveitis

Arthritis

Plasma C-reactive protein (mg/L)†

41-143

100-200

22

17

45-146

Haemoglobin (g/L)

80

90

109

125

80

Total white-cell counts

(109 cells/mL)

2-0

3.7-5.0

1.5

5.0

3.8

Monocytes

0

 

1.9%

1.9%

4.3%

Plasma zinc ( mol/L)‡

180-200

82-96

160-200

175

77

Plasma calprotectin (g/L)§

6.5

1.4, 2.55

9

6.1

1.5

 
†Reference <10 mg/L.  ‡Reference 10-18 mol/L.  §Reference <1 mg/L
 
Adapted from Sampson B, et al. Lancet 2002;360:1742-1745.
 
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