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Table |
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Circadian
Rhythms - Genetic Regulation and Clinical Disorders |
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Volume 18,
Issue 1, 2002 |
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Table 1 - Homologous
genes in Drosophila and mice that play a role in circadian clock
regulation. Adapted from Reppert and Weaver.6
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Drosophila |
Mouse
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period (per)* |
mPeriod1 * |
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mPeriod2 * |
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mPeriod3 * |
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Timeless (tim)* |
None |
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Time-out |
mTimeless** |
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Cryptochromes
(Cry)* |
mCry1*
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mCry2* |
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clock* |
mClock* |
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cycle* |
mBmal1 (MOP3) |
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mBmal2 (MOP9) |
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casein kinases 1 epsilon (TAU)* |
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* mutation results in arrhythmic behavior
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** mutation results in embryonic lethal |
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